Regulation of hyperactivation of hamster spermatozoa by progesterone

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Suppression of Progesterone-enhanced Hyperactivation in Hamster Spermatozoa by γ-aminobutyric Acid

It has been recently shown that mammalian spermatozoa were hyperactivated by steroids, amines and amino acids. In the present study, we investigated whether hyperactivation of hamster sperm is regulated by progesterone (P) and γ-aminobutyric acid (GABA). Although sperm hyperactivation was enhanced by P, GABA significantly suppressed P-enhanced hyperactivation in a dose-dependent manner. Suppres...

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Estrogen suppresses melatonin-enhanced hyperactivation of hamster spermatozoa

Hamster sperm hyperactivation is enhanced by progesterone, and this progesterone-enhanced hyperactivation is suppressed by 17β-estradiol (17βE2) and γ-aminobutyric acid (GABA). Although it has been indicated that melatonin also enhances hyperactivation, it is unknown whether melatonin-enhanced hyperactivation is also suppressed by 17βE2 and GABA. In the present study, melatonin-enhanced hyperac...

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Changes in Motility Parameters of Mouse Spermatozoa in Response to Different Doses of Progesterone during Course of Hyperactivation

The aim of this study was to evaluate changes that occur in motility parameters of progesterone treated mouse spermatozoa during course of hyperactivation. Mouse spermatozoa treated with different doses of progesterone were videotaped after 10 min and 90 min of incubation. For each sperm, one second of movement of the head-midpiece junction was traced from the videotape and for each tracing sev...

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Effects of Different Doses of Progesterone on Motion Parameters of Mouse Spermatozoa During the Course of Hyperactivation

Purpose: To evaluate the changes that occur in the motility parameters of progesterone treated sperms during the course of hyperactivation. Materials and Methods: Spermatozoa treated with different doses of progesterone were videotaped after 10 min and 90 min. For each sperm, 1 sec. of movement of the head-midpiece junction was traced from the videotape. For each tracing, seven motility parame...

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ژورنال

عنوان ژورنال: Reproductive Medicine and Biology

سال: 2008

ISSN: 1445-5781

DOI: 10.1111/j.1447-0578.2008.00202.x